People infected with the SARS-CoV-2 virus, which causes COVID-19, are most contagious two days before, and three days after they develop symptoms, according to a study conducted in China. The research, published in the journal JAMA Internal Medicine, also found that infected individuals were more likely to be asymptomatic if they contracted the virus from a primary case -- the first infected person in an outbreak -- who was also asymptomatic. "In previous studies, viral load has been used as an indirect measure of transmission," said Leonardo Martinez, an assistant professor at Boston University School of Public Health (BUSPH) in the US. "We wanted to see if results from these past studies, which show that that COVID cases are most transmissible a few days before and after symptom onset, could be confirmed by looking at secondary cases among close contacts," Martinez said. The researchers conducted contact tracing and studied COVID-19 transmission among approximately 9,000 close .
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